Dads Also Pass on Mitochondrial DNA, Contrary to Long-Standing Belief

This article from Smithsonian Magazine describes new evidence that some people receive their mitochondrial DNA from the sperm cell rather than the egg cell that made them. This contradicts a longstanding generalization that only egg cells contribute mitochondrial DNA.

This article uses the words mother/maternal and father/paternal to refer to two contributors of genetic material in humans. Consider speaking with your students about other terms that may be more inclusive of all people and their families, such as sperm-derived and egg-derived DNA.

InstaGene Mendelian Inheritance App

The most authentic way to teach Mendelian genetics is to focus on real-life traits in humans and non-human species. The InstaGene app is a user-friendly database of single-locus Mendelian traits in several species. The name of the gene, dominant allele, recessive allele, and source are given. Both allele phenotypes are explicitly named, with neither referred to as “normal”. Many of the alleles code for non-harmful variations, which averts the common association between mutation and disease. The app was created with Glide Apps and can be viewed, copied, and remixed all in a web browser - no app download required.

InstaGene can be used as a teacher reference or it can be given to students for reference while they complete practice problems. A set of sample problems, with model language, is provided below.