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Diagram of Mammalian Sex Determination

December 23, 2019 Sam Long
Image shows the development of testes or ovaries from a bipotential gonad in the first 20 days after conception. Factors shown to be influencing gonadal development include the Sry and Sox9 genes, FGF9, Antimullerian hormone, PGD2, WNT4, RSPO1, FOXL…

Image shows the development of testes or ovaries from a bipotential gonad in the first 20 days after conception. Factors shown to be influencing gonadal development include the Sry and Sox9 genes, FGF9, Antimullerian hormone, PGD2, WNT4, RSPO1, FOXL2, and Follistatin.

This diagram shows basic gene expression and hormone signalling pathways leading to to development of the mammalian gonads. The “dpc” on the x-axis of the graph means days post-conception. This image goes one step further than teaching that “the Y chromosome causes development of testes.”

For an AP Biology class learning about signaling pathways, reading a larger selection from the source article may be useful.

Source: Kashimada, Kenichi, and Peter Koopman. "Sry: the master switch in mammalian sex determination." Development 137.23 (2010): 3921-3930.

In models Tags sex determination, genetics, hormones, anatomy
← Neuroscientists You Should Know: Ben BarresSex Determination – Why So Many Ways of Doing It? →

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